Search results for keratin
Showing 41 results out of 112,071 in All results
Protein sequences
(51,402 results)
P08729
(K2C7_HUMAN)Homo sapiens (Reviewed)
Secondary accession number(s): Q92676, Q9BUD8, Q9Y3R7
P04264
(K2C1_HUMAN)
Keratin, type II cytoskeletal 1
Homo sapiens
(Reviewed)
Secondary accession number(s):
B2RA01, P85925, P86104, Q14720, Q6GSJ0, Q9H298
P05783
(K1C18_HUMAN)
Keratin, type I cytoskeletal 18
Homo sapiens
(Reviewed)
Secondary accession number(s):
Q53G38, Q5U0N8, Q9BW26
Protein families
(51 results)
Keratin
Keratin
Keratin
Keratins are a well known group of intermediate filament proteins. Like actin filaments, keratins are flexible but provide a firm cell skeleton. Unlike actin, however, no known keratins are associated with motor functions. This family represents avian keratin proteins, found in feathers, scale and ...
Keratin, type I cytoskeletal 18
Keratin, type I cytoskeletal 18 (Keratin-18) is one of the major intermediate filament proteins in the human intestinal epithelia. When phosphorylated, it plays a role in filament reorganisation.
Samples & ontologies
(452 results)
keratin filament
Ontology: cellular component
A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of ...
obsolete acidic keratin
Ontology: cellular component
OBSOLETE. A type of intermediate filament.
obsolete basic/neutral keratin
Ontology: cellular component
OBSOLETE. A type of intermediate filament.
Enzymes
(7 results)
Trichoplein keratin filament-binding protein, putative
Trichoplein keratin filament-binding protein, putative
Keratin-associated protein 5-8, putative
Keratin-associated protein 5-8, putative
Peptidase K
Hydrolysis of keratin, and of other proteins with subtilisin-likespecificity. Hydrolyzes peptide amides.
Nucleotide sequences
(29,469 results)
AAB30058
Homo sapiens (human) partial keratin
BAB16373
Paralichthys olivaceus (Japanese flounder) partial keratin
AJ401159
Lampetra fluviatilis mRNA for keratin type II Lfl-K 1 (keratin gene)
Genomes & metagenomes
(7,156 results)
keratin 1
Approved Symbol:
KRT1
Approved Name: keratin 1
Status: (Approved)
Aliases: KRT1A
Locus Type: gene with protein product
Chromosome: 12q13.13
keratin 2
Approved Symbol:
KRT2
Approved Name: keratin 2
Status: (Approved)
Aliases: KRTE
Locus Type: gene with protein product
Chromosome: 12q13.13
keratin 3
Approved Symbol:
KRT3
Approved Name: keratin 3
Status: (Approved)
Aliases: CK3 K3
Locus Type: gene with protein product
Chromosome: 12q13.13
Literature
(20,446 results)
Sedimentation studies of epidermal keratins: keratin A and keratin B.
MATOLTSY AG
(1956 May 25), The Journal of biophysical and biochemical cytology 2 (3) 361-3
Structure of alpha-keratin.
FRASER RD,
MACRAE TP,
ROGERS GE
(1959 Feb 28), Nature 183 (4661) 592-4
Iodination of keratin.
RICHARDS HR,
SPEAKMAN JB
(1953 Apr 25), Nature 171 (4356) 751
Reactions, pathways & diseases
(625 results)
Keratin filament formation
Mammalian keratin filaments are produced by the lateral and longitudinal aggregation of subunits, such as tetrameric protofilaments and octameric protofibrils (Aebi et al. 1983). The extent of ... . 2007). Filaments have a cross-section of 32 keratin molecules (Jones et al. 1997).
Stable Id: R-HSA-6806610
Type: Reaction
Species: Homo sapiens
Formation of hair keratin fibres
... . Approximately 90% of cortical cells contain longitudinally arrayed keratin filaments. These filaments have a surrounding matrix that contains keratin-associated proteins (KAPs) that are involved in ... al., 2010, Gong et al. 2016). KAPs forming extensive disulfide cross-links with keratin filaments ...
Stable Id: R-HSA-6809663
Type: Reaction
Species: Homo sapiens
Keratin type I binds keratin type II
The first step in keratin assembly is the formation of coiled-coil heterodimers consisting of an acidic type I keratin and a basic or neutral type II keratin (Coulombe & Fuchs 1990, Hatzfeld & Webber ... form even in 9M urea (Coulombe & Fuchs 1990). The ~50 nm long middle rod region of keratin protein ...
Stable Id: R-HSA-6805546
Type: Reaction
Species: Homo sapiens
Gene expression
(2,121 results)
KRT35
Ovis aries KRT35, keratin, type I cuticular Ha5 [Source:RefSeq peptide;Acc:NP_001108233], is expressed in 2 baseline experiment(s); breed: Gansu alpine fine wool sheep; developmental stage: juvenile, adult; organism part: inner lining mucosa of the abomasum, abomasum, rumen, skin of back, skin from ...
krt8.2
Xenopus tropicalis krt8.2, keratin 8, type II [Source:Xenbase;Acc:XB-GENE-876686], is expressed in 1 baseline experiment(s); organism part: kidney, liver
LOC102557415
Rattus norvegicus LOC102557415, keratin-associated protein 5-1-like [Source:RGD Symbol;Acc:7596803], is expressed in 1 baseline experiment(s); organism part: spleen, colon; strain: F344/Cr1
Molecular interactions
(179 results)
krt8-krt18
keratin and keratin 18 association measured by antibody affinity
mdm2-if90l_human_pro
Mdm2 coimmunoprecipitates keratin 14 in H1299 cell extracts
kt222_human
Keratin-like protein KRT222
Macromolecular structures
(9 results)
Heterocomplex of coil 2B domains of human intermediate filament proteins, keratin 5 (KRT5) and keratin 14 (KRT14)
CYTOSOLIC PROTEIN x-ray diffraction entry at resolution 3.005
Crystal structure of the keratin-like domain from the MADS transcription factor Sepallata 3
TRANSCRIPTION x-ray diffraction entry at resolution 2.49
Crystal structure of keratin 4 binding domain of surface adhesin Srr-1 of S.agalactiae
CELL ADHESION x-ray diffraction entry at resolution 1.7
Small molecules
(2 results)
EBI web
(16 results)
EMBL European Bioinformatics Institute
... gene, protein or chemical: Examples: blast, keratin, bfl1, Janet Thornton ...
http://www.ebi.ac.uk/
Sorry, this page is not available < EMBL-EBI
Explore the EBI: Examples: blast, keratin, bfl1... We’re sorry but we can’t find the page or file you requested It may have been removed, had its name changed, or be temporarily unavailable. Our web server sees this as a 404 ...
http://www.ebi.ac.uk/not-found
download
... . AEO:JB AEO:JB endocrine gland. keratin-based structure AEO:0000099 Acellular anatomical structure whose predominant constituent is keratin. EHDAA2 ... whose predominant constituent is keratin. chitin-based structure AEO:0000100 ...
http://www.ebi.ac.uk/ols/ontologies/aeo/download
Protein expression data
(136 results)
Incorporation of nonproteinogenic amino acids into bacterial proteome analyzed by unbiased quantitative MS of protein modifications
To study incorporation of nonproteinogenic amino acids in bacterial proteome we performed a global, unbiased protein modification analysis of the E. coli K12 strain with defective editing mechanism of the leucyl tRNA synthetase (LeuRS), which in addition to leucine incorporates a nonproteinogenic amino acid norvaline. We measured widespread loss of ...
Discovery proteomics on cutaneous biopsies
Lyme disease is the most important vector-borne disease in the Northern hemisphere and represents a major public health challenge. The disease diagnosis relies mainly on clinical practice that can be coupled to serological or molecular diagnostics. However the relatively low sensitivity and specificity of the available Lyme diagnostics indicate the ...
Proteomics of GPI-anchored proteins
GPI-anchored proteins (GPI-APs) are an important class of glycoproteins that are tethered to the surface of mammalian cells via the lipid glycosylphosphatidylinositol (GPI). GPI-APs have been implicated in many important cellular functions including cell adhesion, cell signaling, and immune regulation. Proteomic identification of mammalian GPI-APs ...